The Cellets product represents a cellulose material, which combines different properties such as the perfect sphericity, fine particle size distribution, low friability and solubility, and inertness. The experiments were carried out with Cellets 200 granulated celluloses used as a filling material for a laboratory glass column, using diluted dye solution (9-10 mg of dye /L of solution) at adequate initial pH (4.7). The effect of flow rate was investigated, and the modeling of experimental data for dynamic adsorption of Methylene Blue organic dye from aqueous solution in a fixed bed column was studied based on Thomas, and Yoon-Nelson models. The optimal volume of working dye solution per adsorbent mass was determined as higher than 0.01368 m3/day and the adsorption capacity of Cellets 200 celluloses in fixed-bed column study for Methylene Blue dye removal was in the range of 1.375-3.303 mg/g. The obtained results confirm that the tested granulated cellulose can be considered as a good adsorbent into dynamic operating systems, which can be used in the treatment of wastewater containing organic dyes.